Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 12/20 | 0.37 |
| ▸ | GRK2 | P25098 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910483 | 0.89 | SDHB (0.38) | SDHBGRK2P2RX7ROCK2MKNK1 | |
| SCHEMBL20985699 | 0.87 | SDHB (0.36) | SDHBGRK2P2RX7ROCK2BRD4 | |
| SCHEMBL20985672 | 0.83 | SDHB (0.37) | SDHBGRK2P2RX7ROCK2MKNK1 | |
| SCHEMBL30526073 | 0.83 | SDHB (0.37) | SDHBGRK2P2RX7ROCK2MKNK1 | |
| SCHEMBL29976336 | 0.81 | SDHB (0.46) | SDHBGRK2ROCK2BRD4 | |
| SCHEMBL20985623 | 0.81 | SDHB (0.46) | SDHBGRK2ROCK2BRD4 | |
| SCHEMBL20985723 | 0.80 | SDHB (0.45) | SDHB | |
| SCHEMBL20985681 | 0.75 | SDHB (0.54) | SDHB | |
| SCHEMBL29975895 | 0.75 | SDHB (0.54) | SDHB | |
| SCHEMBL26313233 | 0.74 | SDHB (0.49) | SDHBGRK2ROCK2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| US-20210309647-A1 | Apoptosis Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SDHB 3/4885GRK2 3248/4885P2RX7 4784/4885 |
| US-20210309647-A1 | Apoptosis Inhibitors | BAX, SDHA, SDHB | SDHB 3/4885GRK2 3248/4885P2RX7 4784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.