Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910493 | 0.76 | KDM4E (0.43) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL28910479 | 0.74 | KDM4E (0.44) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL28910513 | 0.74 | SDHB (0.68) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL28910482 | 0.72 | KDM4E (0.61) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL28910512 | 0.71 | KDM4E (0.45) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL11000674 | 0.69 | ALDH1A1 (0.61) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL20985732 | 0.65 | KDM4E (0.49) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL31314434 | 0.65 | KDM4E (0.60) | KDM4EMAPK1HSD17B10TDP1TSHR | |
| SCHEMBL28580846 | 0.63 | NPC1 (0.69) | KDM4EHSD17B10TDP1ALDH1A1LMNA | |
| SCHEMBL19805733 | 0.62 | KDM4E (0.60) | KDM4EMAPK1HSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |