Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306288 | 0.87 | — | — | |
| SCHEMBL28307468 | 0.87 | PDE2A (0.32) | MAPTKMT2AHSD17B10 | |
| SCHEMBL28910510 | 0.87 | TP53 (0.39) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29976298 | 0.81 | SDHB (0.42) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL19805932 | 0.81 | SDHB (0.42) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL28306356 | 0.73 | SDHB (0.35) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL28306419 | 0.73 | SDHB (0.46) | KDM4EALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL19805740 | 0.72 | SDHB (0.46) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29976021 | 0.72 | SDHB (0.46) | KDM4EALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29975980 | 0.69 | SDHB (0.45) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |