Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657078 | 0.97 | ESR1 (0.42) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL434194 | 0.81 | ESR1 (0.44) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL9590359 | 0.77 | ESR1 (0.41) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL8827054 | 0.77 | ESR1 (0.41) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL2464760 | 0.77 | ESR1 (0.46) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL3971800 | 0.75 | MAPT (0.39) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL56621 | 0.73 | ALDH1A1 (0.36) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL63526 | 0.73 | ESR1 (0.70) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL239179 | 0.73 | ESR1 (0.48) | ESR1ESR2MAPTCES2CES1 | |
| SCHEMBL92396 | 0.73 | ESR1 (0.48) | ESR1ESR2MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117684183-A | Metal organic catalyst, preparation method and application thereof | 贵研铂业股份有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-113278230-A | Halogen-free flexible material | 河北金威新型建筑材料有限公司 | 2021-08-20 | — | — | CN | claimed |
| US-20190263765-A1 | SYNERGISTIC ANTICOAGULANT COMPOSITION | WISYS TECH FOUNDATION INC (US) | 2019-08-29 | — | — | US | claimed |
| US-7781560-B2 | Curable mixture of an alkoxyalkyl endcapped polysiloxane prepared by reacting a vinyl-terminated polysiloxane with a mono- or disiloxyalkyldisiloxane, an alkylhydrogenpolysiloxane, and organosilicon compound, and a hydrosilation catalyst; has good adhesion to unclean aluminum die castings | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-08-24 | — | — | US | claimed |
| US-20100160356-A1 | NOVEL CYCLOBUTYL COMPOUNDS AS KINASE INHIBITORS | MERCK PATENT GESELLSCHAFT (DE) | 2010-06-24 | — | — | US | claimed |
| EP-1863875-B1 | SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF | MOMENTIVE PERFORMANCE MAT INC (DE) | 2009-12-09 | — | — | EP | claimed |
| US-20090068475-A1 | Self-Adhesive Addition-Crosslinking Silicon Rubber Blends, A Method For The Production Thereof, Methods For Producing Composite Moulded Parts And The Use Thereof | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-03-12 | — | — | US | claimed |
| EP-2004651-A2 | NOVEL CYCLOBUTYL COMPOUNDS AS KINASE INHIBITORS | MERCK PATENT GmbH (DE) | 2008-12-24 | — | — | EP | claimed |
| JP-2008537967-A | — | — | 2008-10-02 | — | — | JP | claimed |
| EP-1863875-A1 | SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF | Momentive Performance Materials GmbH (DE) | 2007-12-12 | — | — | EP | claimed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | claimed |
| US-5217633-A | LOW-TEMPERATURE LUBRICATING OIL | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | claimed |
| EP-0201176-B1 | THERMOSETTING RESIN COMPOSITION | Toray Silicone Company Limited (JP) | 1993-03-17 | — | — | EP | claimed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | claimed |
| US-5010148-A | Combined with a silicate resin having trimethylsiloxy and methylvinylsiloxy groups; halogen-free | GENERAL ELECTRIC COMPANY (US) | 1991-04-23 | — | — | US | claimed |
| EP-0415070-A2 | Flame retardant aromatic polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-4663397-A | Thermosetting resin composition | TORAY SILICONE CO., LTD. (JP) | 1987-05-05 | — | — | US | claimed |
| EP-0201176-A2 | Thermosetting resin composition | Toray Silicone Company Limited (JP) | 1986-11-12 | — | — | EP | claimed |
| US-4267117-A | INTERMEDIATES FOR 1A-HYDROXYLATED CALCIFEROLS | THE UPJOHN COMPANY (US) | 1981-05-12 | — | — | US | claimed |
| US-4206131-A | 1A-HYDROXYLATED CALCIFEROLS | THE UPJOHN COMPANY (US) | 1980-06-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160356-A1 | NOVEL CYCLOBUTYL COMPOUNDS AS KINASE INHIBITORS | MAP3K20, MAP3K1, MAP3K2 | ESR1 3514/4885ESR2 2229/4885MAPT 1828/4885 |
| US-20190263765-A1 | SYNERGISTIC ANTICOAGULANT COMPOSITION | PROC, F2, VKORC1 | ESR1 3262/4885ESR2 1778/4885MAPT 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.