SCHEMBL434194

SCHEMBL434194

C[Si]([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
MAPT P10636 1/20 0.39
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
NR1H2 P55055 2/20 0.35
NR1H3 Q13133 2/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.33
ELANE P08246 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ATM Q13315 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28911 0.81 ESR1 (0.44) ESR1ESR2MAPTCES2CES1
SCHEMBL28657078 0.79 ESR1 (0.42) ESR1ESR2MAPTCES2CES1
SCHEMBL9590359 0.77 ESR1 (0.41) ESR1ESR2MAPTCES2CES1
SCHEMBL8827054 0.77 ESR1 (0.41) ESR1ESR2MAPTCES2CES1
SCHEMBL2464760 0.77 ESR1 (0.46) ESR1ESR2MAPTCES2CES1
SCHEMBL3971800 0.75 MAPT (0.39) ESR1ESR2MAPTCES2CES1
SCHEMBL56621 0.73 ALDH1A1 (0.36) ESR1ESR2MAPTCES2CES1
SCHEMBL439492 0.73 ESR1 (0.48) ESR1ESR2MAPTCES2CES1
SCHEMBL2169977 0.73 ESR1 (0.48) ESR1ESR2MAPTCES2CES1
SCHEMBL92396 0.73 ESR1 (0.48) ESR1ESR2MAPTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117684183-A Metal organic catalyst, preparation method and application thereof 贵研铂业股份有限公司 2024-03-12 CN claimed
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN claimed
EP-1863875-B1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MAT INC (DE) 2009-12-09 EP claimed
US-20090068475-A1 Self-Adhesive Addition-Crosslinking Silicon Rubber Blends, A Method For The Production Thereof, Methods For Producing Composite Moulded Parts And The Use Thereof MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2009-03-12 US claimed
JP-2008537967-A 2008-10-02 JP claimed
EP-1863875-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF Momentive Performance Materials GmbH (DE) 2007-12-12 EP claimed
WO-2006100098-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2006-09-28 WO claimed
EP-1352043-B1 IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID DOW CORNING (US) 2005-03-16 EP claimed
EP-1352043-A1 IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID Dow Corning Corporation (US) 2003-10-15 EP claimed
US-6530316-B2 Continuously operating press utilizing a phenyl-endblocked polydiorganosiloxane-polyphenylorganosiloxane random copolymer fluid DOW CORNING CORPORATION 2003-03-11 US claimed
US-20020129718-A1 Continuously operating press utilizing a phenyl-endblocked polydiorganosiloxane-polyphenylorganosiloxane random copolymer fluid DOW CORNING CORPORATION 2002-09-19 US claimed
WO-2002066586-A1 IMPROVED CONTINUOUSLY OPERATING PRESS UTILIZING A PHENYL-ENDBLOCKED POLYDIORGANOSILOXANE-POLPHENYLORGANOSILOXANE RANDOM COPOLYMER FLUID DOW CORNING CORPORATION (US) 2002-08-29 WO claimed
US-5294737-A Hydrolysis, cyclization, condensation THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) 1994-03-15 US claimed
US-4650885-A Process for preparing derivatives of naphthazarin NIPPON OIL CO., LTD. (JP) 1987-03-17 US claimed
CN-114222779-B Polyorganosiloxane containing epoxy group, curable resin composition containing the same, and cured product thereof 三菱化学株式会社 2024-06-18 CN disclosed
WO-2024111390-A1 COMPOUND AND METHOD FOR PRODUCING SAME 学校法人帝京大学 2024-05-30 WO disclosed
US-20240132675-A1 POLYMER HAVING METAL-OXYGEN-METAL BOND AS PRIMARY CHAIN, COMPOSITION THEREOF, SOLID MATERIAL AND PRODUCTION METHOD THEREOF, AND ELECTRONIC COMPONENT AND FIBER TORAY INDUSTRIES, INC. (JP) 2024-04-25 US disclosed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed
US-4113690-A Silicone elastomers containing alkoxysiloxanols SWS SILICONES CORPORATION (US) 1978-09-12 US disclosed
US-3996188-A AROMATIC ACIDS DOW CORNING CORPORATION (US) 1976-12-07 US disclosed