Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444016 | 0.78 | MEN1 (0.52) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL28643962 | 0.75 | MEN1 (0.48) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL21596408 | 0.75 | MEN1 (0.48) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL27271884 | 0.73 | KIF11 (0.49) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL28701872 | 0.72 | MEN1 (0.44) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL28434571 | 0.71 | MEN1 (0.43) | MEN1KMT2ANR1H4ATMGAA | |
| SCHEMBL28913034 | 0.69 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL10681896 | 0.68 | MEN1 (0.47) | MEN1KMT2ANR1H4KIF11POLB | |
| SCHEMBL27487685 | 0.66 | CA2 (0.57) | MEN1KMT2ANR1H4GAAL3MBTL1 | |
| SCHEMBL28400285 | 0.66 | KIF11 (0.47) | MEN1KMT2ANR1H4ATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315423-A | Substituted aryl compounds | 先声药业有限公司 | 2022-11-08 | — | — | CN | disclosed |