Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119009 | 0.82 | SRD5A2 (0.45) | LTA4HCALM1 | |
| SCHEMBL27746677 | 0.76 | TDP1 (0.48) | LTA4HMAOB | |
| SCHEMBL28149724 | 0.76 | CALM1 (0.42) | LTA4HMEN1KMT2ANPC1RAB9A | |
| SCHEMBL542478 | 0.75 | LTA4H (0.58) | LTA4HSIGMAR1MEN1KMT2ACA4 | |
| SCHEMBL457684 | 0.75 | CA1 (0.42) | LTA4HSIGMAR1NPC1RAB9A | |
| SCHEMBL7532413 | 0.75 | CALM1 (0.52) | LTA4HIDH1CALM1 | |
| SCHEMBL570480 | 0.74 | LTA4H (1.00) | LTA4HSIGMAR1MEN1KMT2ACA4 | |
| SCHEMBL18705795 | 0.74 | MEN1 (0.37) | LTA4HMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7019024 | 0.74 | LTA4H (0.52) | LTA4HSIGMAR1CA4IDH1MAOB | |
| SCHEMBL27746705 | 0.73 | LTA4H (0.43) | LTA4HSIGMAR1MAOBCALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108047114-B | Halogenated trifluoromethyl pyrrole derivative and preparation method and application thereof | 华东师范大学 | 2021-05-25 | — | — | CN | disclosed |