Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581257 | 0.83 | KMT2A (0.43) | KMT2AMEN1MAPTGSTP1GSTM2 | |
| SCHEMBL93759 | 0.78 | TXNRD1 (0.54) | KMT2AMEN1GSTP1GSTM2POLB | |
| Hydrochloric Acid SCHEMBL3785878 | 0.76 | TXNRD1 (0.53) | KMT2AMEN1GSTP1GSTM2POLB | |
| Hydrogen Sulfide SCHEMBL16111783 | 0.76 | TXNRD1 (0.53) | KMT2AMEN1GSTP1GSTM2POLB | |
| Pyridine SCHEMBL26106735 | 0.70 | TXNRD1 (0.46) | KMT2AMEN1GSTP1GSTM2ALDH1A1 | |
| Gamma-Aminobutyric Acid SCHEMBL5574736 | 0.68 | GSTP1 (0.44) | KMT2AMEN1GSTP1GSTM2ALDH1A1 | |
| SCHEMBL6759398 | 0.66 | TXNRD1 (0.42) | KMT2AMEN1GSTP1GSTM2ALDH1A1 | |
| SCHEMBL7332645 | 0.66 | MEN1 (0.37) | KMT2AMEN1MAPTGSTP1GSTM2 | |
| Norleucine SCHEMBL28902593 | 0.66 | GRM8 (0.43) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL1161371 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939960-B | Carbonyl azetidine substituted NBD fluorescent dye and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2023-04-14 | — | — | CN | disclosed |
| CN-112939960-A | Carbonyl azetidine substituted NBD fluorescent dye and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | disclosed |