Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 10/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MYC | P01106 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93759 | 0.81 | TXNRD1 (0.54) | GSTP1GSTM2MEN1KMT2AMYC | |
| Hydrogen Sulfide SCHEMBL16111783 | 0.80 | TXNRD1 (0.53) | GSTP1GSTM2MEN1KMT2AMYC | |
| Hydrochloric Acid SCHEMBL3785878 | 0.80 | TXNRD1 (0.53) | GSTP1GSTM2MEN1KMT2AMYC | |
| Pyridine SCHEMBL26106735 | 0.76 | TXNRD1 (0.46) | GSTP1GSTM2MEN1KMT2AMYC | |
| Norleucine SCHEMBL28902593 | 0.76 | GRM8 (0.43) | MEN1KMT2AMYCRECQLALDH1A1 | |
| SCHEMBL7332645 | 0.74 | MEN1 (0.37) | GSTP1GSTM2MEN1KMT2AMYC | |
| Aminocaproic Acid SCHEMBL29028429 | 0.71 | MEN1 (0.41) | MEN1KMT2ARECQLALDH1A1CYP2D6 | |
| SCHEMBL7714790 | 0.70 | GSTP1 (0.54) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL6759398 | 0.69 | TXNRD1 (0.42) | GSTP1GSTM2MEN1KMT2AMYC | |
| SCHEMBL14617994 | 0.69 | GSTM2 (0.72) | GSTP1GSTM2MEN1KMT2AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7172877-B2 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-06 | — | — | US | disclosed |
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-20 | — | — | US | disclosed |
| US-20040209317-A1 | Methods and compositions for peptide and protein labeling | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233389-A1 | Methods and compositions for peptide and protein labeling | HLCS, BTD, QPCTL | GSTP1 3394/4885GSTM2 4223/4885MEN1 1564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.