Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 9/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 7/20 | 0.36 |
| ▸ | SMARCA4 | P51532 | 7/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196249 | 0.71 | MKNK1 (0.47) | SMN1; SMN2PBRM1SMARCA2SMARCA4KDM1A | |
| SCHEMBL22493647 | 0.66 | USP7 (0.35) | USP7 | |
| SCHEMBL26471836 | 0.66 | USP7 (0.35) | USP7 | |
| SCHEMBL28907422 | 0.66 | NOS3 (0.37) | USP7 | |
| SCHEMBL26686534 | 0.66 | USP7 (0.35) | USP7 | |
| SCHEMBL23901911 | 0.66 | USP7 (0.35) | USP7 | |
| SCHEMBL27941436 | 0.66 | GSK3A (0.42) | SMN1; SMN2PBRM1SMARCA2SMARCA4KDM1A | |
| SCHEMBL27718025 | 0.65 | CHRM2 (0.46) | SMN1; SMN2KDM1ACHRM2CHRM4CHRM5 | |
| Potassium Ion SCHEMBL28907435 | 0.65 | USP7 (0.34) | USP7 | |
| SCHEMBL18081028 | 0.65 | PBRM1 (0.60) | PBRM1SMARCA2SMARCA4IKBKBNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353509-A | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-11-18 | — | — | CN | disclosed |