Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.46 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.46 |
| ▸ | INPP5B | P32019 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859933 | 0.86 | INPPL1 (0.46) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL6832733 | 0.84 | INPPL1 (0.45) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL1548297 | 0.78 | INPPL1 (0.52) | INPPL1INPP5AINPP5BSRCALDH1A1 | |
| SCHEMBL31059274 | 0.75 | MEN1 (0.31) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9328494 | 0.75 | MEN1 (0.31) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL10916653 | 0.75 | L3MBTL1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL1160044 | 0.74 | — | — | |
| SCHEMBL780023 | 0.74 | CA2 (0.37) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2847955 | 0.74 | MAPT (0.31) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL2719418 | 0.74 | INPPL1 (0.43) | INPPL1INPP5AINPP5BSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103173194-A | Stable imidazoline solutions | AFTON CHEMICAL CORP | 2013-06-26 | — | — | CN | disclosed |
| US-7682526-B2 | Stable imidazoline solutions | AFTON CHEMICAL CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| CN-101024629-A | Stable imidazoline solutions | AFTON CHEMICAL CORP (US) | 2007-08-29 | — | — | CN | disclosed |
| EP-1806343-A2 | Stable imidazoline solutions | Afton Chemical Corporation (US) | 2007-07-11 | — | — | EP | disclosed |
| US-20070145333-A1 | Stable imidazoline solutions | AFTON CHEMICAL CORPORATION | 2007-06-28 | — | — | US | disclosed |