Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 3/20 | 0.41 |
| ▸ | CHUK | O15111 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25436660 | 0.82 | KDM4E (0.44) | BCAT2IKBKBCHUKPDK2KDM4E | |
| SCHEMBL18092820 | 0.81 | STK10 (0.44) | PDK2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2832469 | 0.76 | BCAT2 (0.62) | BCAT2IKBKBCHUKHNF4APDK2 | |
| SCHEMBL27599960 | 0.73 | AKR1C2 (0.44) | BCAT2IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL27600108 | 0.72 | PDK2 (0.41) | BCAT2IKBKBPDK2KDM4EMEN1 | |
| SCHEMBL27600133 | 0.72 | AKR1C2 (0.43) | BCAT2IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL27635465 | 0.71 | BCAT2 (0.47) | BCAT2IKBKBCHUKPDK2RORC | |
| SCHEMBL5131382 | 0.70 | KMT2A (0.46) | BCAT2IKBKBPDK2RORCRORB | |
| SCHEMBL29838619 | 0.70 | HNF4A (0.72) | BCAT2IKBKBCHUKHNF4AKDM4E | |
| SCHEMBL8888647 | 0.70 | HNF4A (0.72) | BCAT2IKBKBCHUKHNF4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504902-A | 5-chloro salicylamide derivatives, preparation method thereof and application thereof as medicaments | 广东药科大学 | 2022-12-23 | — | — | CN | claimed |
| CN-115504902-A | 5-chloro salicylamide derivatives, preparation method thereof and application thereof as medicaments | 广东药科大学 | 2022-12-23 | — | — | CN | disclosed |