Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916557 | 0.98 | HPGD (0.67) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23564897 | 0.83 | HPGD (0.58) | HPGDRAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL17974502 | 0.82 | PHGDH (0.71) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28916556 | 0.81 | RAB9A (0.57) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28916559 | 0.81 | CES2 (0.54) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL969583 | 0.81 | HPGD (0.96) | HPGDALDH1A1LMNAUSP2ALOX12 | |
| SCHEMBL24185725 | 0.81 | HPGD (0.96) | HPGDALDH1A1LMNAUSP2ALOX12 | |
| SCHEMBL5564719 | 0.81 | HPGD (0.66) | HPGDALDH1A1LMNAUSP2POLB | |
| SCHEMBL28916562 | 0.79 | CES2 (0.56) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28917068 | 0.79 | CES2 (0.56) | HPGDRAB9AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504946-B | Method for synthesizing alpha-ketoamide compound | 武汉工程大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115504946-A | Method for synthesizing alpha-keto amide compound | 武汉工程大学 | 2022-12-23 | — | — | CN | disclosed |