Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917640 | 0.99 | LTA4H (0.62) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917626 | 0.88 | LTA4H (0.56) | LTA4HMCHR1HRH3BACE1 | |
| SCHEMBL28917705 | 0.88 | LTA4H (0.59) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917648 | 0.88 | KDM4E (0.54) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917652 | 0.87 | LTA4H (0.55) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917650 | 0.86 | KDM4E (0.52) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917888 | 0.86 | LTA4H (0.60) | LTA4HKDM4EALDH1A1SMN1; SMN2MCHR1 | |
| SCHEMBL28917692 | 0.79 | LMNA (0.47) | KDM4EALDH1A1HRH3 | |
| SCHEMBL15474805 | 0.79 | HRH3 (0.76) | LTA4HKDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL14970714 | 0.79 | HRH3 (0.76) | LTA4HKDM4EALDH1A1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229091-B | 1, 5-disubstituted indole derivatives with leukotriene A4 hydrolase inhibition effect and application thereof | 天津科技大学 | 2022-11-22 | — | — | CN | disclosed |