Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | DHODH | Q02127 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12034449 | 0.80 | CDC7 (0.69) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL289878 | 0.79 | TRPM8 (0.56) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL290029 | 0.79 | ALDH1A1 (0.60) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL289644 | 0.77 | KDM4E (0.74) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL289421 | 0.77 | ALDH1A1 (0.64) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL289847 | 0.77 | KDM4E (0.64) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL1976780 | 0.77 | ALOX15 (0.58) | ALDH1A1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL289540 | 0.77 | KDM4E (0.54) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL4464882 | 0.76 | CDC7 (0.73) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL289647 | 0.75 | CDC7 (0.64) | CDC7DBF4ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |