Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689225 | 0.86 | LMNA (0.46) | PTPN1LMNAKMT2ACA12CA9 | |
| SCHEMBL9042229 | 0.86 | LMNA (0.46) | PTPN1LMNAKMT2ACA12CA9 | |
| SCHEMBL6806279 | 0.79 | KMT2A (0.54) | PTPN1LMNAKMT2AMEN1CA12 | |
| SCHEMBL5852237 | 0.79 | ALDH1A1 (0.49) | PTPN1LMNAKMT2ACA12CA9 | |
| SCHEMBL15910890 | 0.78 | LMNA (0.54) | PTPN1LMNAKMT2ACA12CA9 | |
| SCHEMBL3654422 | 0.78 | TSHR (0.50) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28918502 | 0.77 | LMNA (0.50) | PTPN1LMNAKMT2AMEN1CA12 | |
| SCHEMBL11807375 | 0.77 | KMT2A (0.51) | PTPN1LMNAKMT2AMEN1CA12 | |
| SCHEMBL5400501 | 0.77 | KMT2A (0.51) | PTPN1LMNAKMT2AMEN1CA12 | |
| SCHEMBL3379309 | 0.76 | SMN1; SMN2 (0.41) | PTPN1KMT2AMEN1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593068-B | Intermediate of ROR gamma inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |