Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MGAM | O43451 | 3/20 | 0.50 |
| ▸ | SI | P14410 | 3/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683335 | 0.93 | GAA (0.52) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL28918556 | 0.86 | HSD17B10 (0.51) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL7022121 | 0.82 | MAOB (0.50) | GAACA9CA12CA1CA2 | |
| SCHEMBL10603429 | 0.77 | GAA (0.46) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL6685604 | 0.75 | GAA (0.49) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL3281348 | 0.75 | MAOB (0.50) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL9227196 | 0.75 | GAA (0.49) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL9206553 | 0.75 | ALDH1A1 (0.50) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL6679976 | 0.75 | GAA (0.44) | GAAMGAMSIMGAM2CA9 | |
| SCHEMBL28918561 | 0.74 | ACHE (0.56) | CA9CA12CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368333-A | Compound containing ibuprofen-coumarin skeleton and application thereof | 湖北医药学院 | 2022-11-22 | — | — | CN | disclosed |