Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | F12 | P00748 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683335 | 0.81 | GAA (0.52) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL6226548 | 0.81 | GPR35 (0.49) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL10602195 | 0.79 | GAA (0.46) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL1561361 | 0.78 | GAA (0.53) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL6685604 | 0.78 | GAA (0.49) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL14199261 | 0.78 | MAOB (0.53) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL9227196 | 0.78 | GAA (0.49) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL28918552 | 0.77 | GAA (0.45) | MAOBMAOAGAAMGAMSI | |
| SCHEMBL28918554 | 0.75 | GAA (0.50) | MAOAGAAMGAMSIMGAM2 | |
| SCHEMBL28918556 | 0.75 | HSD17B10 (0.51) | GAAMGAMSIMGAM2F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709496-B2 | Antibacterial agents | GLAXO GROUP LIMITED (GB) | 2010-05-04 | — | — | US | disclosed |
| US-20090054418-A1 | Antibacterial Agents | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054418-A1 | Antibacterial Agents | MRPL21, ELANE, SPOUT1 | MAOB 2498/4885MAOA 2135/4885GAA 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.