Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.54 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918687 | 1.00 | ACE (0.54) | ACEACE2PRCPFAPREN | |
| SCHEMBL31159646 | 0.97 | ACE (0.51) | ACEACE2PRCPFAPREN | |
| SCHEMBL21302901 | 0.97 | ACE (0.51) | ACEACE2PRCPFAPREN | |
| SCHEMBL28918729 | 0.92 | ACE (0.58) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL28918708 | 0.92 | ACE (0.58) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL18373911 | 0.92 | ACE (0.58) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL28748915 | 0.92 | ACE (0.58) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL28918671 | 0.92 | ACE (0.58) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL31109309 | 0.91 | ACE (0.57) | ACEACE2PRCPOPRM1OPRD1 | |
| SCHEMBL28748865 | 0.91 | ACE (0.57) | ACEACE2PRCPOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352067-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2024-10-24 | — | — | US | disclosed |
| CN-115368438-A | Pyrrolidine amide derivatives and methods of making and using the same | 成均馆大学校产学协力团 | 2022-11-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240352067-A1 | PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME | NOD2, SI, APC | ACE 1293/4885ACE2 1072/4885PRCP 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.