SCHEMBL2891876

SCHEMBL2891876

O=C(O)c1cc(Cl)c(Cl)c(Cl)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 8/20 0.57
AKR1C1 Q04828 8/20 0.57
AKR1C4 P17516 2/20 0.57
AKR1C3 P42330 2/20 0.57
HPGD P15428 4/20 0.55
HSD17B10 Q99714 4/20 0.55
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 1/20 0.55
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
PKM P14618 1/20 0.55
HTT P42858 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 4/20 0.52
MAPK1 P28482 1/20 0.52
TTR P02766 1/20 0.46
AKR1B1 P15121 1/20 0.45
CASP1 P29466 2/20 0.44
TP53 P04637 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30632048 1.00 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL30296240 0.96 AKR1C2 (0.53) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL1513825 0.86 AKR1C2 (0.63) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL11763697 0.82 HSD17B10 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL14273026 0.82 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL1437003 0.81 CYP3A4 (0.48) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL2149302 0.81 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL7005963 0.81 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL28883530 0.81 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
Fluoride SCHEMBL6445648 0.79 CYP3A4 (0.47) AKR1C2AKR1C1AKR1C4AKR1C3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214437895-U Trichlorosalicylic acid hydrolysis acid gas absorption device capable of automatically cleaning 山东博苑医药化学股份有限公司 2021-10-22 CN claimed
CN-106893343-B Cyanine compound, colored curable resin composition containing same, color filter and display device containing same 东友精细化工有限公司 2022-11-18 CN disclosed
CN-214437895-U Trichlorosalicylic acid hydrolysis acid gas absorption device capable of automatically cleaning 山东博苑医药化学股份有限公司 2021-10-22 CN disclosed
CN-214437895-U Trichlorosalicylic acid hydrolysis acid gas absorption device capable of automatically cleaning 山东博苑医药化学股份有限公司 2021-10-22 CN disclosed
US-20210302320-A1 MOISTURE DETECTION METHOD AND MOISTURE DETECTION SYSTEM MORESCO CORPORATION (JP) 2021-09-30 US disclosed
CN-112437878-A Moisture detection method and moisture detection system 株式会社MORESCO 2021-03-02 CN disclosed
CN-111200935-A Dicamba compositions with reduced spray drift potential 美国陶氏益农公司 2020-05-26 CN disclosed
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 US disclosed
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 US disclosed
WO-2019079236-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 WO disclosed
US-8283280-B2 Reforming catalyst preparation by dry impregnation IFP Energies Nouvelles (FR) 2012-10-09 US disclosed
US-20100285953-A1 REFORMING CATALYST PREPARATION BY DRY IMPREGNATION IFP (FR) 2010-11-11 US disclosed
US-7234827-B2 Chemiluminescent device LUMICA CORPORATION (JP) 2007-06-26 US disclosed
US-20040141310-A1 Chemiluminescent device LUMICA CORPORATION (JP) 2004-07-22 US disclosed
EP-1018927-A1 LIGHTING ELEMENT FOR VISUAL OR PHOTOGRAPHIC MEDICAL EXAMINATION Laboratoires Piette International S.A. (BE) 2000-07-19 EP disclosed
WO-1999016342-A1 LIGHTING ELEMENT FOR VISUAL OR PHOTOGRAPHIC MEDICAL EXAMINATION LABORATOIRES PIETTE INTERNATIONAL S.A. (BE) 1999-04-08 WO disclosed
US-5194666-A Intermediates for chemiluminescent agents, chlorination, esterification AMERICAN CYANAMID COMPANY (US) 1993-03-16 US disclosed
US-5194666-A Intermediates for chemiluminescent agents, chlorination, esterification AMERICAN CYANAMID COMPANY (US) 1993-03-16 US disclosed
US-4308395-A Processes for preparing 3,5,6-trichlorosalicylic acid and esters thereof AMERICAN CYANAMID COMPANY (US) 1981-12-29 US disclosed
US-3973001-A Tissue cell stimulating blood extracts SOLCO BASEL AG (CH) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DDT, CDA, SGMS1 AKR1C2 3685/4885AKR1C1 3661/4885AKR1C4 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.