SCHEMBL30296240

SCHEMBL30296240

O=C(O)c1cc(Cl)c(Cl)c(Cl)c1O.[Al].[Zr]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 8/20 0.53
AKR1C1 Q04828 8/20 0.53
AKR1C4 P17516 2/20 0.53
AKR1C3 P42330 2/20 0.53
HPGD P15428 4/20 0.52
HSD17B10 Q99714 4/20 0.52
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
MAPT P10636 1/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
TSHR P16473 4/20 0.48
MAPK1 P28482 1/20 0.48
TTR P02766 1/20 0.43
AKR1B1 P15121 1/20 0.42
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2891876 0.96 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL30632048 0.96 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL1513825 0.83 AKR1C2 (0.63) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL11763697 0.78 HSD17B10 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL14273026 0.78 AKR1C2 (0.57) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL1437003 0.78 CYP3A4 (0.48) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL2149302 0.78 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL7005963 0.78 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
SCHEMBL28883530 0.78 AKR1C2 (0.52) AKR1C2AKR1C1AKR1C4AKR1C3HPGD
Fluoride SCHEMBL6445648 0.76 CYP3A4 (0.47) AKR1C2AKR1C1AKR1C4AKR1C3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115737481-A Sweat-inhibiting, sterilizing and deodorizing composition 深圳市理然化妆品有限公司 2023-03-07 CN claimed
CN-115737481-A Sweat-inhibiting, sterilizing and deodorizing composition 深圳市理然化妆品有限公司 2023-03-07 CN disclosed