Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 9/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 9/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006728 | 0.83 | KEAP1 (0.42) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL30632048 | 0.81 | AKR1C2 (0.57) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL2891876 | 0.81 | AKR1C2 (0.57) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL1513825 | 0.81 | AKR1C2 (0.63) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL30296240 | 0.78 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL7070814 | 0.78 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL8683261 | 0.77 | KEAP1 (0.44) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL28883530 | 0.76 | AKR1C2 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL2149302 | 0.76 | AKR1C2 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL27592650 | 0.75 | ALDH1A1 (0.58) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894784-B1 | 4-FLUOROSALICYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | IHARA CHEMICAL IND CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6166246-A | 4-fluorosalicyclic acid derivative and process for production thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0894784-A1 | 4-FLUOROSALICYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1999-02-03 | — | — | EP | disclosed |