Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919053 | 0.87 | MAPT (0.61) | KMT2ATHRBMAPTCYP2C9TP53 | |
| SCHEMBL28919037 | 0.83 | MAPT (0.52) | THRBMAPTCYP2C9TP53PKM | |
| SCHEMBL10902432 | 0.82 | CYP2C9 (0.67) | KMT2ACYP2C9LMNAMEN1POLB | |
| SCHEMBL28919074 | 0.82 | PKM (0.62) | MAPTPKMPKLRPOLB | |
| SCHEMBL10900999 | 0.80 | CYP2C9 (0.71) | KMT2ACYP2C9MEN1POLBNPSR1 | |
| SCHEMBL20188098 | 0.80 | HPGD (0.65) | KMT2AMAPTCYP2C9LMNAMEN1 | |
| SCHEMBL22015905 | 0.80 | HPGD (0.65) | KMT2AMAPTCYP2C9LMNAMEN1 | |
| SCHEMBL2943824 | 0.79 | KMT2A (0.61) | KMT2AMAPTTP53LMNAMEN1 | |
| SCHEMBL10901799 | 0.78 | CYP2C9 (0.68) | KMT2AMAPTCYP2C9MEN1POLB | |
| SCHEMBL28919018 | 0.77 | THRB (0.51) | KMT2ATHRBMAPTTP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |