Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919024 | 0.89 | POLB (0.49) | THRBTP53MAPTOGAKDM4E | |
| SCHEMBL28919047 | 0.84 | PKM (0.54) | MAPTALDH1A1PKMPKLRKMT2A | |
| SCHEMBL3000559 | 0.77 | LMNA (0.59) | THRBMAPTALDH1A1HSD17B10PKM | |
| SCHEMBL3018745 | 0.77 | PKM (0.47) | MAPTALDH1A1HSD17B10PKMPKLR | |
| SCHEMBL28919041 | 0.77 | KMT2A (0.60) | THRBTP53MAPTPKMPKLR | |
| SCHEMBL10466693 | 0.77 | OGA (0.56) | MAPTOGAALDH1A1HPGDPKM | |
| SCHEMBL7185606 | 0.77 | ALDH1A1 (0.62) | MAPTOGAKDM4EALDH1A1HPGD | |
| SCHEMBL3008963 | 0.77 | LMNA (0.56) | MAPTALDH1A1HSD17B10PKMPKLR | |
| SCHEMBL28603507 | 0.76 | THRB (0.53) | THRBTP53MAPTPKMPKLR | |
| SCHEMBL3015551 | 0.76 | AR (0.53) | MAPTALDH1A1HSD17B10PKMPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521272-B | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2023-07-21 | — | — | CN | disclosed |
| CN-115521272-A | Benzenesulfonyl piperazine compound and medical application thereof | 河北省人民医院 | 2022-12-27 | — | — | CN | disclosed |