Pyrazole

Pyrazole

SCHEMBL28919862

Brc1cccnc1Br.c1cn[nH]c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
AXL P30530 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CDC25B P30305 1/20 0.32
S1PR4 O95977 1/20 0.31
NUDT1 P36639 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MAPT P10636 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580420 0.81
SCHEMBL212732 0.81
SCHEMBL31088692 0.79
Hydrochloric Acid SCHEMBL27751934 0.79
Bromide SCHEMBL8154448 0.79
Pyrazole SCHEMBL28861614 0.74 KDM4E (0.34) SMN1; SMN2LMNANPC1RAB9AKDM4E
Pyrazole SCHEMBL4576298 0.72 NUDT1 (0.41) AXLSMN1; SMN2LMNAADRA1ANUDT1
Bromobenzene SCHEMBL3471724 0.71 ALDH1A1 (0.50) SMN1; SMN2NPC1RAB9AMAPTMAPK1
Pyrazole SCHEMBL5664483 0.71
Pyrazole SCHEMBL7671561 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112280008-A Bridged asymmetric benzodiazole and/or pyridine diazole birceptor polymer semiconductor and preparation method and application thereof 华南协同创新研究院 2021-01-29 CN claimed
CN-112280008-B Bridged asymmetric benzodiazole and/or pyridine diazole birceptor polymer semiconductor and preparation method and application thereof 东莞伏安光电科技有限公司 2022-12-20 CN disclosed
CN-112280008-A Bridged asymmetric benzodiazole and/or pyridine diazole birceptor polymer semiconductor and preparation method and application thereof 华南协同创新研究院 2021-01-29 CN disclosed