SCHEMBL289199

SCHEMBL289199

OCCCCCC(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL467974 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL120683 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20267799 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL238123 0.97
SCHEMBL95867 0.94
Water SCHEMBL29080231 0.90
SCHEMBL9193186 0.90 SMN1; SMN2 (0.35) LMNAALDH1A1HSD17B10MEN1KMT2A
Chloroform SCHEMBL10841676 0.88 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL30569675 0.83
SCHEMBL30899237 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5196094-A Separation of 1,1,1-trichloroethane from the lower alcohols by extractive distillation Berg, Lloyd (US) 1993-03-23 US claimed
JP-51149221-A None JP disclosed
CN-113189213-A Method for measuring molecular weight and molecular weight distribution of polysaccharides in ginseng traditional Chinese medicine 天津中医药大学 2021-07-30 CN disclosed
US-9096531-B2 Fused imidazole derivative TOA EIYO LTD. (JP) 2015-08-04 US disclosed
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP disclosed
EP-2578573-A1 FUSED IMIDAZOLE DERIVATIVE TOA Eiyo Ltd. (JP) 2013-04-10 EP disclosed
US-20130065896-A1 FUSED IMIDAZOLE DERIVATIVE TOA EIYO LTD. (JP) 2013-03-14 US disclosed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US disclosed
EP-2459569-A1 INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE Merial Limited (US) 2012-06-06 EP disclosed
EP-2427429-A1 CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS Abbott GmbH & Co. KG (DE) 2012-03-14 EP disclosed
WO-1997035845-A1 SUBSTITUTED 1-METHYL-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-10-02 WO disclosed
WO-1997001543-A1 1-AMINO-3-BENZYLURACILS BASF AKTIENGESELLSCHAFT (DE) 1997-01-16 WO disclosed
EP-0374771-B1 Production method for PvuI restriction endonuclease TOYO BOSEKI (JP) 1994-04-13 EP disclosed
US-5196094-A Separation of 1,1,1-trichloroethane from the lower alcohols by extractive distillation Berg, Lloyd (US) 1993-03-23 US disclosed
EP-0108422-A1 Flux removal solvent blend THE DOW CHEMICAL COMPANY (US) 1984-05-16 EP disclosed
US-4330533-A Novel polysaccharide and hypocholesterol composition containing the same MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1982-05-18 US disclosed
US-4230800-A METHANOL AS CARBON SOURCE MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1980-10-28 US disclosed
US-4075339-A BACTERICIDES, VIRICIDES, ANTIBIOTICS UNIVERSITY OF ILLINOIS FOUNDATION (US) 1978-02-21 US disclosed
JP-S51149221-A PREPARATION OF 3,3-DIMETHYL-4,6,6- TRIHALO-4-HEXENOIC ESTERS SUMITOMO CHEM CO LTD 1976-12-22 JP disclosed
US-3987035-A GELDANAMYCIN DERIVATIVES, BACTERICIDES, VIRICIDES UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065896-A1 FUSED IMIDAZOLE DERIVATIVE CACNA1E, CACNA1G, CACNA1A LMNA 4407/4885ALDH1A1 4252/4885HSD17B10 4346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.