SCHEMBL467974

SCHEMBL467974

OCCCCCCCCC(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289199 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL120683 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20267799 1.00 LMNA (0.38) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL238123 0.97
SCHEMBL95867 0.94
Water SCHEMBL29080231 0.90
SCHEMBL9193186 0.90 SMN1; SMN2 (0.35) LMNAALDH1A1HSD17B10MEN1KMT2A
Chloroform SCHEMBL10841676 0.88 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL30569675 0.83
SCHEMBL30899237 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116640798-A Salt stress analysis method of alfalfa gene promoter 鲁东大学 2023-08-25 CN claimed
WO-2024054768-A2 BRASSICA CYTOPLASMIC MALE STERILITY (CMS) FERTILITY RESTORER NUCLEIC ACIDS, MARKERS, METHODS, AND ZYGOSITY ASSAYS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-03-14 WO disclosed
CN-116640798-A Salt stress analysis method of alfalfa gene promoter 鲁东大学 2023-08-25 CN disclosed
US-11319599-B2 Genetic loci associated with reproductive growth phenotypes in soybean and methods of use PIONEER HI-BRED INTERNATIONAL, INC. 2022-05-03 US disclosed
US-11225668-B2 Modified FRT recombination site libraries and methods of use PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-01-18 US disclosed
US-20210348179-A1 COMPOSITIONS AND METHODS FOR REGULATING GENE EXPRESSION FOR TARGETED MUTAGENESIS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-11-11 US disclosed
US-11028453-B2 QTLs associated with and methods for identifying lodging resistance in soybean PIONEER HI-BRED INTERNATIONAL, INC. 2021-06-08 US disclosed
US-10709727-B2 Antiviral drugs IDAC THERANOSTICS, INC. (JP) 2020-07-14 US disclosed
US-10577666-B2 Compositions associated with soybean reproductive growth and methods of use PIONEER HI-BRED INTERNATIONAL, INC. (US) 2020-03-03 US disclosed
US-20190194673-A1 MODIFIED FRT RECOMBINATION SITE LIBRARIES AND METHODS OF USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2019-06-27 US disclosed
EP-0587798-A4 INSECTICIDAL PROTEINS AND METHOD FOR PLANT PROTECTION. DOWELANCO (US) 1995-04-19 EP disclosed
US-5399496-A Industrial production of polypeptides HOFFMAN-LAROCHE INC. (US) 1995-03-21 US disclosed
CN-1095723-A Nucleic acid preparation method and nucleic acid Ganoderma oral liquid thereof PAN GUANGWAN (CN) 1994-11-30 CN disclosed
EP-0587798-A1 INSECTICIDAL PROTEINS AND METHOD FOR PLANT PROTECTION DOWELANCO (US) 1994-03-23 EP disclosed
EP-0133473-B1 In vivo labelling of polynucleotide sequences ENZO BIOCHEM INC (US) 1994-03-23 EP disclosed
WO-1992021753-A1 INSECTICIDAL PROTEINS AND METHOD FOR PLANT PROTECTION DOWELANCO (US) 1992-12-10 WO disclosed
US-4994373-A Hybridization, labeling ENZO BIOCHEM, INC. (US) 1991-02-19 US disclosed
US-4987065-A GENETIC ENGINEERING ENZO BIOCHEM, INC. (US) 1991-01-22 US disclosed
US-4503218-A BACTERICIDE E. R. SQUIBB & SONS, INC. (US) 1985-03-05 US disclosed
EP-0133473-A2 In vivo labelling of polynucleotide sequences ENZO BIOCHEM, INC. (US) 1985-02-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10709727-B2 Antiviral drugs DOCK2, DOCK11, HAVCR2 LMNA 2107/4885ALDH1A1 2649/4885HSD17B10 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.