Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177013 | 0.74 | CA2 (0.52) | CA2MAPTPOLBLMNA | |
| SCHEMBL3762799 | 0.72 | CA12 (0.56) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL3842057 | 0.72 | CA12 (0.56) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL29688324 | 0.72 | CA12 (0.56) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL3769067 | 0.72 | CA12 (0.56) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL13077397 | 0.71 | LMNA (0.53) | KMT2AMEN1GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4365231 | 0.69 | CYP3A4 (0.68) | CA2CA12CA1CA9GAA | |
| SCHEMBL23886945 | 0.69 | CA12 (0.51) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL4338551 | 0.69 | CA12 (0.51) | CA2CA12CA1CA9KMT2A | |
| SCHEMBL7627388 | 0.67 | KEAP1 (0.67) | CA2CA12CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |