SCHEMBL2892041

SCHEMBL2892041

O=C(CC(F)(F)F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 10/20 0.40
CES1 P23141 9/20 0.39
CES2 O00748 4/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA2 P00918 1/20 0.38
PLOD2 O00469 1/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4976795 0.77 PLOD2 (0.38) FAAHCES1CES2MEN1CYP1A2
SCHEMBL14769297 0.75 LIPA (0.36)
SCHEMBL8406316 0.75 KMT2A (0.33) FAAHCES1CES2MEN1CYP1A2
SCHEMBL25007292 0.75 FAAH (0.42) FAAHCES1CES2MEN1CYP1A2
SCHEMBL2000632 0.75 CES1 (0.30) CES1
SCHEMBL16173984 0.73 FAAH (0.36) FAAHCES1CES2MEN1CYP1A2
SCHEMBL4486281 0.73
SCHEMBL17586556 0.73 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL183178 0.72 PLOD2 (0.46) FAAHCES1CES2MEN1CYP1A2
SCHEMBL1058273 0.72 PLA2G4A (0.38) CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114409514-A Synthetic method of 1,1,1,4,4, 4-hexafluoro-2-butanone 西安近代化学研究所 2022-04-29 CN claimed
US-20050188697-A1 Fluorinated ketone and fluorinated ethers as working fluids for thermal energy conversion HONEYWELL CORPORATION 2005-09-01 US claimed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
CN-114409514-B Synthesis method of 1, 4-hexafluoro-2-butanone 西安近代化学研究所 2023-07-18 CN disclosed
CN-114409514-A Synthetic method of 1,1,1,4,4, 4-hexafluoro-2-butanone 西安近代化学研究所 2022-04-29 CN disclosed
CN-114409514-A Synthetic method of 1,1,1,4,4, 4-hexafluoro-2-butanone 西安近代化学研究所 2022-04-29 CN disclosed
CN-114409514-A Synthetic method of 1,1,1,4,4, 4-hexafluoro-2-butanone 西安近代化学研究所 2022-04-29 CN disclosed
EP-2551333-B1 LUBRICATING OIL COMPOSITION FOR CHILLER IDEMITSU KOSAN CO (JP) 2020-12-16 EP disclosed
CN-110114358-A Novel compound and pharmacologically acceptable salt thereof 明治制果药业株式会社 2019-08-09 CN disclosed
EP-2138559-B1 LUBRICATING OIL COMPOSITION FOR REFRIGERATORS IDEMITSU KOSAN CO (JP) 2018-12-19 EP disclosed
EP-2551333-A1 LUBRICATING OIL COMPOSITION FOR CHILLER Idemitsu Kosan Co., Ltd. (JP) 2013-01-30 EP disclosed
US-20130012419-A1 LUBRICATING OIL COMPOSITION FOR CHILLER IDEMITSU KOSAN CO., LTD. (JP) 2013-01-10 US disclosed
US-20130012420-A1 LUBRICATING OIL COMPOSITION FOR CHILLER IDEMITSU KOSAN CO., LTD. (JP) 2013-01-10 US disclosed
US-20100281912-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINE AND COMPRESSOR USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-11-11 US disclosed
EP-2233555-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINE AND COMPRESSOR USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-09-29 EP disclosed
US-20100133463-A1 LUBRICATING OIL COMPOSITION FOR REFRIGERATORS IDEMITSU KOSAN CO., LTD. (JP) 2010-06-03 US disclosed
EP-2138559-A1 LUBRICATING OIL COMPOSITION FOR REFRIGERATORS Idemitsu Kosan Co., Ltd. (JP) 2009-12-30 EP disclosed
US-20050188697-A1 Fluorinated ketone and fluorinated ethers as working fluids for thermal energy conversion HONEYWELL CORPORATION 2005-09-01 US disclosed
US-20050188697-A1 Fluorinated ketone and fluorinated ethers as working fluids for thermal energy conversion HONEYWELL CORPORATION 2005-09-01 US disclosed