Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935331 | 0.85 | LMNA (0.50) | TDP1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL5678485 | 0.81 | LMNA (0.53) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL27267377 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL26179405 | 0.80 | TSHR (0.46) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL21673638 | 0.79 | TSHR (0.48) | TDP1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL4050408 | 0.78 | LMNA (0.52) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL26045534 | 0.76 | TSHR (0.48) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL8604492 | 0.76 | LMNA (0.47) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL26179407 | 0.76 | SMN1; SMN2 (0.39) | TDP1ALDH1A1TSHRMAPK1HIF1A | |
| SCHEMBL28686366 | 0.75 | SMN1; SMN2 (0.56) | TDP1ALDH1A1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248399-A | O-amino aromatic amide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-08-13 | — | — | CN | disclosed |