SCHEMBL28922018

SCHEMBL28922018

C=C(C)C(=O)OC(Cc1cccc(C(F)(F)F)c1)C(O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.44
HTR2B P41595 3/20 0.44
HTR2C P28335 2/20 0.44
ACP3 P15309 1/20 0.42
MAOB P27338 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX1 P07099 3/20 0.41
CES2 O00748 1/20 0.41
ADRA2C P18825 2/20 0.41
SLC6A4 P31645 2/20 0.41
ADRA1A P35348 2/20 0.41
DRD3 P35462 2/20 0.41
USP2 O75604 2/20 0.41
CYP3A4 P08684 2/20 0.41
NR1I2 O75469 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28630457 0.83 ACP3 (0.43) HTR2AHTR2BHTR2CACP3MEN1
SCHEMBL14648181 0.79 IDO1 (0.49) ACP3MEN1KMT2AEPHX1CES2
SCHEMBL14648282 0.76 IDO1 (0.56) ACP3MEN1KMT2AEPHX1CES2
SCHEMBL28631469 0.74 HTR2A (0.55) HTR2AHTR2BHTR2CACP3EPHX1
SCHEMBL2030657 0.73 PRKCA (0.58) ACP3MAOBMAPT
SCHEMBL28629138 0.71 ACACB (0.44) EPHX1PPARGPPARA
SCHEMBL13235906 0.71 HTR2A (0.64) HTR2AHTR2BHTR2CACP3MAOB
SCHEMBL5706555 0.71 HTR2A (0.59) HTR2AHTR2BHTR2CMAOBEPHX1
SCHEMBL5706562 0.71 HTR2A (0.59) HTR2AHTR2BHTR2CMAOBEPHX1
SCHEMBL5706539 0.71 HTR2A (0.59) HTR2AHTR2BHTR2CMAOBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641831-B Monomers, polymers, preparation method and use thereof 东莞东阳光医疗智能器件研发有限公司 2021-09-10 CN disclosed