SCHEMBL2030657

SCHEMBL2030657

C=C(C)C(=O)OCc1cccc(C(F)(F)F)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.58
PRKCD Q05655 1/20 0.58
MAOB P27338 4/20 0.56
MMP1 P03956 1/20 0.54
MMP12 P39900 1/20 0.54
HTT P42858 2/20 0.53
MAPT P10636 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
IDO1 P14902 2/20 0.53
NR4A2 P43354 2/20 0.51
FFAR4 Q5NUL3 2/20 0.48
FFAR1 O14842 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.47
ACP3 P15309 1/20 0.47
POLB P06746 1/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12184255 0.91 PRKCA (0.52) PRKCAPRKCDMAOBMMP1MMP12
SCHEMBL11390199 0.86 PRKCA (0.58) PRKCAPRKCDMAOBMMP1MMP12
SCHEMBL13292600 0.85 IDO1 (0.47) PRKCAPRKCDMAOBMAPTIDO1
SCHEMBL2660451 0.85 PRKCA (0.63) PRKCAPRKCDMAOBMMP1MMP12
SCHEMBL10322053 0.85 ALDH1A1 (0.48) MAOBMMP12L3MBTL1
SCHEMBL20762777 0.83 PRKCA (0.42) PRKCAPRKCDMAOBMMP1MMP12
SCHEMBL10885394 0.82 MAOB (0.52) MAOBMMP1MMP12MAPTIDO1
SCHEMBL20267723 0.82 IDO1 (0.62) PRKCAPRKCDMAOBMMP1MMP12
SCHEMBL21112022 0.81 HCAR2 (0.55) MAOBMMP1MMP12MAPTIDO1
SCHEMBL1904651 0.80 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11945890-B2 Fluorinated PVC copolymer compositions for increased ultraviolet protection Mexichem Specialty Resins Inc. (US) 2024-04-02 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
US-20230303739-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. 2023-09-28 US disclosed
EP-4249519-A1 FLUORINATED PVC COPOLYMER COMPOSITIONS FOR INCREASED ULTRAVIOLET PROTECTION Mexichem Specialty Resins Inc. (US) 2023-09-27 EP disclosed
US-11649633-B2 Self-cleaning cool roof system U.S. SILICA COMPANY (US) 2023-05-16 US disclosed
US-20200325683-A1 SELF-CLEANING COOL ROOF SYSTEM U.S. SILICA COMPANY (US) 2020-10-15 US disclosed
US-10704262-B2 Self-cleaning cool roof system U.S. SILICA COMPANY (US) 2020-07-07 US disclosed
US-10584278-B2 Proppant having amphiphobic coatings and methods for making and using same CARBO CERAMICS INC. (US) 2020-03-10 US disclosed
US-20190225878-A1 PROPPANT HAVING AMPHIPHOBIC COATINGS AND METHODS FOR MAKING AND USING SAME CARBO CERAMICS INC. 2019-07-25 US disclosed
CN-105567260-A Print Functionalized photoreactive compounds ROLIC AG 2016-05-11 CN disclosed
CN-101268168-B Functionalized photoreactive compounds ROLIC AG (CH) 2016-01-20 CN disclosed
US-20120296029-A1 FLUORINE-CONTAINING MULTIFUNCTIONAL MICROSPHERES AND USES THEREOF QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-11-22 US disclosed
US-20120264884-A1 Amphiphobic Surfaces from Block Copolymers QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-10-18 US disclosed
US-20110224356-A1 LOW SURFACE ENERGY BLOCK CO-POLYMER PREPARATION METHODS AND APPLICATIONS ARKEMA INC. (US) 2011-09-15 US disclosed
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
US-20080312377-A1 Low Surface Energy Block Copolymer Preparation Methods and Applications ARKEMA, INC. (US) 2008-12-18 US disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
CN-101268168-A Functionalized photoreactive compounds ROLIC AG (CH) 2008-09-17 CN disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C PRKCA 2691/4885PRKCD 2605/4885MAOB 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.