Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19836690 | 0.71 | SMN1; SMN2 (0.40) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL29172743 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL20740530 | 0.68 | CSNK1E (0.35) | CDK4CDK6 | |
| SCHEMBL5735229 | 0.67 | CYP2A6 (0.31) | — | |
| SCHEMBL1180513 | 0.66 | — | — | |
| SCHEMBL9939224 | 0.65 | — | — | |
| SCHEMBL6772300 | 0.65 | — | — | |
| SCHEMBL21077368 | 0.63 | EGFR (0.33) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL14718463 | 0.63 | ALOX5 (0.32) | — | |
| SCHEMBL5733210 | 0.63 | KDR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |