SCHEMBL5735229

SCHEMBL5735229

CCCC[Sn](CCCC)(CCCC)c1cnc(C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9939224 0.83
SCHEMBL6772300 0.83
SCHEMBL14718463 0.80 ALOX5 (0.32)
SCHEMBL5733210 0.80 KDR (0.30)
SCHEMBL3208582 0.78 GABRP (0.40) CYP3A4
SCHEMBL1180513 0.77
SCHEMBL5733976 0.75 LMNA (0.34) CYP2C9CYP2C19
SCHEMBL5733664 0.74 KDR (0.31)
SCHEMBL5733424 0.73 HCAR2 (0.32)
SCHEMBL1456734 0.73 MAPT (0.38) CYP2A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070713-B1 QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2006-10-18 EP disclosed
US-6335447-B1 BACTERICIDES TOYAMA CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
EP-1070713-A1 QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2001-01-24 EP disclosed