Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26170172 | 0.84 | PARP1 (0.48) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL25206972 | 0.80 | USP30 (0.52) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL3963418 | 0.77 | POLB (0.58) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL25151279 | 0.74 | USP30 (0.49) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL28923421 | 0.74 | USP30 (0.56) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL26650838 | 0.73 | LMNA (0.45) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL26651051 | 0.73 | PARP1 (0.47) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL30826701 | 0.73 | PARP1 (0.53) | LMNATHRBPOLBEPHX1PARP1 | |
| SCHEMBL16269787 | 0.73 | HDAC4 (0.52) | LMNATHRBPOLBUSP30EPHX1 | |
| SCHEMBL4603719 | 0.72 | HDAC4 (0.63) | POLBEPHX1HDAC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132646-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |