Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KAT7 | O95251 | 1/20 | 0.31 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398011 | 0.91 | KCNA5 (0.46) | KCNA5SGMS2MAPK1EPAS1 | |
| SCHEMBL12292166 | 0.85 | KCNA5 (0.41) | KCNA5SGMS2PDE4BEPAS1LRRK2 | |
| SCHEMBL292526 | 0.83 | KCNA5 (0.64) | KCNA5SGMS2ALDH1A1GAAMAPT | |
| SCHEMBL12292170 | 0.82 | KCNA5 (0.40) | KCNA5SGMS2ALDH1A1GAAMAPT | |
| SCHEMBL1711260 | 0.80 | KCNA5 (0.41) | KCNA5SGMS2RAB9AALDH1A1GAA | |
| SCHEMBL13903694 | 0.76 | KDM4E (0.34) | KCNA5MAPTLMNA | |
| SCHEMBL14397963 | 0.75 | KCNA5 (0.41) | KCNA5SGMS2EPAS1LRRK2 | |
| SCHEMBL2238634 | 0.75 | HCRTR1 (0.36) | KCNA5KMT2A | |
| SCHEMBL14397620 | 0.74 | KCNA5 (0.40) | KCNA5SGMS2MAPTEPAS1MEN1 | |
| SCHEMBL10167494 | 0.72 | HCRTR1 (0.36) | KCNA5MAPK1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8017554-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest | BASF SE (DE) | 2011-09-13 | — | — | US | disclosed |
| US-8017554-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest | BASF SE (DE) | 2011-09-13 | — | — | US | disclosed |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2064196-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | KCNA5 1882/4885SGMS2 3649/4885MAPK1 349/4885 |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BPNT1, AADAT, BCAT1 | KCNA5 552/4885SGMS2 4174/4885MAPK1 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.