Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 14/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923685 | 1.00 | GAA (0.50) | GAATRPV3PKMCFTRPDCD1 | |
| SCHEMBL22345794 | 0.84 | GAA (0.56) | GAATRPV3PKMPDCD1CD274 | |
| SCHEMBL22345795 | 0.84 | GAA (0.56) | GAATRPV3PKMPDCD1CD274 | |
| SCHEMBL22345802 | 0.82 | TRPV3 (0.49) | TRPV3CD274 | |
| SCHEMBL26618708 | 0.82 | TRPV3 (0.49) | TRPV3CD274 | |
| SCHEMBL22345799 | 0.82 | TRPV3 (0.49) | TRPV3CD274 | |
| SCHEMBL30850022 | 0.82 | TRPV3 (0.49) | TRPV3CD274 | |
| SCHEMBL18137673 | 0.68 | ADH1B (0.37) | — | |
| SCHEMBL1864095 | 0.68 | KDM4E (0.32) | TRPV3 | |
| SCHEMBL14921437 | 0.66 | GAA (0.70) | GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474349-A | Hydroxypyridooxazepine heptatrienes as NRF2 activators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-01 | — | — | CN | disclosed |