Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454756 | 0.84 | PRKAB2 (0.40) | PARP1KEAP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL21835399 | 0.84 | PRKAB2 (0.40) | PARP1KEAP1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL28965423 | 0.83 | PARP1 (0.40) | PARP1PARP2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL28288790 | 0.83 | KDM4E (0.41) | PARP1PIM1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL28288776 | 0.82 | LIPG (0.45) | MEN1KMT2APTGDR2 | |
| SCHEMBL27992014 | 0.79 | ALDH1A1 (0.46) | KMT2A | |
| SCHEMBL1765144 | 0.79 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL30423645 | 0.79 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL18863213 | 0.79 | PTGDR2 (0.51) | KEAP1PTGDR2 | |
| SCHEMBL31444311 | 0.76 | HTR2A (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678815-B | N-benzyl benzamide derivative and preparation method and pharmaceutical application thereof | 中国药科大学 | 2022-11-29 | — | — | CN | disclosed |