SCHEMBL28923936

SCHEMBL28923936

c1ccccc2c(ccc1)CSS2

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
GAA P10253 2/20 0.34
RYR2 Q92736 2/20 0.33
HPGD P15428 2/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ACHE P22303 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B3 P37058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL450053 0.97
SCHEMBL10580638 0.95 ALDH1A1 (0.34) ALDH1A1GAARYR2HPGDMAPT
Cyclopentane SCHEMBL28685011 0.93 TSHR (0.36) ALDH1A1GAARYR2HPGDMAPT
SCHEMBL1718843 0.85 RYR2 (0.32) ALDH1A1GAARYR2TSHR
SCHEMBL28602086 0.85 ALDH1A1 (0.30) ALDH1A1GAA
SCHEMBL29025314 0.83 TSHR (0.30) TSHR
SCHEMBL29025270 0.83 LMNA (0.30) LMNAHTTNPSR1
SCHEMBL10827179 0.81 PTPN5 (0.36) ALDH1A1GAARYR2HPGDMAPT
SCHEMBL16972817 0.78 MAOA (0.31)
SCHEMBL9149 0.73 RYR2 (0.36) ALDH1A1GAARYR2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699026-B Method for preparing cyclododecane disulfide 伊士曼化工公司 2021-10-01 CN disclosed