SCHEMBL2892397

SCHEMBL2892397

O=C1C=C(N(Cc2cnc(Cl)c(F)c2)CC(F)F)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026050 0.90 ALDH1A1 (0.30)
SCHEMBL2895152 0.89
SCHEMBL2892775 0.87
SCHEMBL1165111 0.87
SCHEMBL29394548 0.82 KDM1A (0.32)
SCHEMBL123283 0.82 KDM1A (0.32)
SCHEMBL119650 0.81 NR3C2 (0.32)
SCHEMBL120285 0.81 DRD2 (0.31)
SCHEMBL119799 0.80 CTSL (0.30)
SCHEMBL13903055 0.79 RECQL (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130303376-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2013-11-14 US claimed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US claimed
EP-2090168-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-08-19 EP claimed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP claimed
EP-2004636-B1 Substituted enaminocarbonyl compounds used as insecticides BAYER IP GMBH (DE) 2015-04-22 EP disclosed
EP-2004636-B1 Substituted enaminocarbonyl compounds used as insecticides BAYER IP GMBH (DE) 2015-04-22 EP disclosed
US-20130303376-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2013-11-14 US disclosed
US-8084452-B2 Substituted enaminocarbonyl compounds used as insecticides BAYER CROPSCIENCE AG (DE) 2011-12-27 US disclosed
US-8084452-B2 Substituted enaminocarbonyl compounds used as insecticides BAYER CROPSCIENCE AG (DE) 2011-12-27 US disclosed
US-8084452-B2 Substituted enaminocarbonyl compounds used as insecticides BAYER CROPSCIENCE AG (DE) 2011-12-27 US disclosed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2004636-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES Bayer CropScience AG (DE) 2008-12-24 EP disclosed
WO-2008148483-A1 INSECTICIDE COMPOSITIONS HAVING AN IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2008-12-11 WO disclosed
EP-2000027-A1 Insecticide compounds with improved effect Bayer CropScience AG (DE) 2008-12-10 EP disclosed
EP-2000027-A1 Insecticide compounds with improved effect Bayer CropScience AG (DE) 2008-12-10 EP disclosed
WO-2007115646-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed
WO-2007115646-A1 SUBSTITUTED ENAMINOCARBONYL COMPOUNDS USED AS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2007-10-18 WO disclosed