Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ME2 | P23368 | 6/20 | 0.48 |
| ▸ | ME1 | P48163 | 6/20 | 0.48 |
| ▸ | ME3 | Q16798 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542788 | 0.86 | ALDH1A1 (0.47) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL28106920 | 0.85 | GAA (0.56) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL28304654 | 0.85 | L3MBTL1 (0.62) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL20640028 | 0.85 | MAPT (0.50) | MAPTGAAALDH1A1USP2KMT2A | |
| SCHEMBL28096400 | 0.84 | ALDH1A1 (0.50) | MAPTGAAKDM4EALDH1A1USP2 | |
| Hydrochloric Acid SCHEMBL10436132 | 0.83 | L3MBTL1 (0.60) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL348122 | 0.83 | MEN1 (0.54) | MAPTGAAKDM4EKMT2ALMNA | |
| SCHEMBL3914229 | 0.83 | AKR1C3 (0.51) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL29771394 | 0.82 | GFER (0.51) | MAPTGAAKDM4EALDH1A1USP2 | |
| SCHEMBL27922475 | 0.79 | KDM4E (0.52) | MAPTGAAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536602-A | Preparation method of posaconazole intermediate | 成都海博为药业有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-114594192-A | Method for detecting chloroaniline and chloronitroaniline isomers in posaconazole starting material | 山东大学 | 2022-06-07 | — | — | CN | claimed |
| CN-115536602-A | Preparation method of posaconazole intermediate | 成都海博为药业有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-114594192-A | Method for detecting chloroaniline and chloronitroaniline isomers in posaconazole starting material | 山东大学 | 2022-06-07 | — | — | CN | disclosed |