Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.35 |
| ▸ | XIAP | P98170 | 3/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924312 | 0.78 | NOTUM (0.39) | NOTUMHSD17B3XIAPBIRC2ALDH1A1 | |
| SCHEMBL28731112 | 0.74 | NOTUM (0.39) | NOTUMHSD17B3ALDH1A1LMNAHTT | |
| SCHEMBL19411736 | 0.74 | PIK3CD (0.49) | NOTUMHSD17B3LMNABRD4KMT2A | |
| SCHEMBL6527995 | 0.73 | NOTUM (0.62) | NOTUMHSD17B3ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28732262 | 0.72 | NOTUM (0.39) | NOTUMHSD17B3XIAPBIRC2ALDH1A1 | |
| SCHEMBL28924178 | 0.71 | XIAP (0.36) | XIAPBIRC2ALDH1A1LMNAHTT | |
| SCHEMBL6037236 | 0.70 | NOTUM (0.48) | NOTUMHSD17B3ALDH1A1LMNAKMT2A | |
| SCHEMBL28924152 | 0.70 | BRD4 (0.37) | NOTUMHSD17B3ALDH1A1LMNABRD4 | |
| SCHEMBL28924231 | 0.68 | ALDH1A1 (0.36) | XIAPBIRC2ALDH1A1LMNAKMT2A | |
| SCHEMBL28924176 | 0.67 | ADRB2 (0.36) | XIAPBIRC2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824573-B | Method for synthesizing cyanoalkylindoline by N-allylaniline cyanoalkylation | 昆明学院 | 2022-05-10 | — | — | CN | claimed |
| CN-109824573-B | Method for synthesizing cyanoalkylindoline by N-allylaniline cyanoalkylation | 昆明学院 | 2022-05-10 | — | — | CN | disclosed |