SCHEMBL2892450

SCHEMBL2892450

CCCCN1CC(C(=O)O)CC1=O

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.60
POLB P06746 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.57
MEN1 O00255 1/20 0.53
CYP2C19 P33261 1/20 0.53
KMT2A Q03164 1/20 0.53
HTT P42858 1/20 0.49
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
MAPT P10636 1/20 0.49
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8293341 1.00 L3MBTL1 (0.60) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL8292876 0.95 POLB (0.58) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL14477978 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL15082405 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL8084202 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL119623 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL8084223 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL8076306 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL14477954 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19
SCHEMBL2890516 0.94 POLB (0.56) L3MBTL1POLBSMN1; SMN2MEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118742283-A Cosmetic or dermatological composition comprising a merocyanine and gamma-butyrolactone and/or gamma-butyrolactam 莱雅公司 2024-10-01 CN disclosed
US-20240238188-A1 OILY COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20240238188-A1 OILY COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-18 US disclosed
WO-2023110767-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A GAMMA-BUTYROLACTONE AND/OR A GAMMA-BUTYROLACTAM L'OREAL (FR) 2023-06-22 WO disclosed
EP-2734180-B1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES OREAL (FR) 2021-03-31 EP disclosed
EP-2579842-B1 COMPOSITION COMPRISING AT LEAST ONE 2-PYRROLIDONE FUNCTIONALIZED IN THE 4 POSITION WITH A CARBOXYLIC ACID OR AMIDE, AND AT LEAST ONE DIRECT DYE OR A PIGMENT FOR DYEING KERATIN FIBRES ORÉAL L (FR) 2016-03-30 EP disclosed
US-20140294743-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES L'OREAL (FR) 2014-10-02 US disclosed
US-20140294743-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES L'OREAL (FR) 2014-10-02 US disclosed
US-8585779-B2 Composition comprising at least one 2-pyrrolidone functionalized in the 4 position with a carboxylic acid or amide, and at least one direct dye or a pigment for dyeing keratin fibres L'OREAL (FR) 2013-11-19 US disclosed
US-8585779-B2 Composition comprising at least one 2-pyrrolidone functionalized in the 4 position with a carboxylic acid or amide, and at least one direct dye or a pigment for dyeing keratin fibres L'OREAL (FR) 2013-11-19 US disclosed
WO-2008132195-A1 ANTI-FOULING COATING COMPOSITIONS CONTAINING A CARBOXYL-FUNCTIONAL ORGANOSILICONE AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2008-11-06 WO disclosed
EP-1660447-B1 CYCLIC AMINE BACE-1 INHIBITORS HAVING A HETEROCYCLIC SUBSTITUENT SCHERING CORP (US) 2008-07-30 EP disclosed
WO-2005014540-A1 CYCLIC AMINE BASE-1 INHIBITORS HAVING A HETEROCYCLIC SUBSTITUENT SCHERING CORPORATION (US) 2005-02-17 WO disclosed
EP-1180513-A1 CYCLIC AMIDE COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-02-20 EP disclosed
US-4987210-A COMPLEXING IODINE AND WATER-INSOLUBLE DRUGS TO MAKE THEM MORE SOLUBLE GAF CHEMICALS CORPORATION (US) 1991-01-22 US disclosed
US-4985521-A COPOLYMERS, COMPLEXES WITH WATER INSOLUBLE MOLECULES GAF CHEMICALS CORPORATION (US) 1991-01-15 US disclosed
US-4946967-A CHEMICAL INTERMEDIATES FOR HIGH MOLECULAR WEIGHT ACYCLIC ESTER OR AMIDE GAF CHEMICALS CORPORATION (US) 1990-08-07 US disclosed
WO-1990005131-A1 POLYMERIZABLE DERIVATIVES OF 5-OXO-PYRROLINE CARBOXYLIC ACID, POLYMERS THEREOF AND METHODS OF PREPARATION GAF CHEMICALS CORPORATION (US) 1990-05-17 WO disclosed
EP-0069512-B1 SALTS OF N-SUBSTITUTED-2-PYRROLIDONE-4-CARBOXYLIC ACIDS AS HUMECTANTS PFIZER INC. (US) 1986-06-04 EP disclosed
EP-0069512-A2 Salts of N-substituted-2-pyrrolidone-4-carboxylic acids as humectants PFIZER INC. (US) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238188-A1 OILY COSMETIC CUTA, HES1, SMO L3MBTL1 806/4885POLB 1580/4885SMN1; SMN2 1566/4885
US-20140294743-A1 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES KRT18, LAGE3, TYR L3MBTL1 4454/4885POLB 2028/4885SMN1; SMN2 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.