SCHEMBL305780

SCHEMBL305780

C=CCO[Si](NCc1ccccc1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH7 P40394 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 3/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.34
ATM Q13315 1/20 0.34
HTT P42858 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28924922 0.81 CYP3A4 (0.46) ADH1BADH1CADH1AADH7ALDH1A1
Cyclopropane SCHEMBL1138573 0.76 CYP3A4 (0.42) ALDH1A1CYP3A4MAPTKDM4ECYP2D6
SCHEMBL2811190 0.76 ALOX15 (0.35) ADH1BADH1CADH1AADH7SMN1; SMN2
Hydrochloric Acid SCHEMBL28487523 0.74 MEN1 (0.43) ADH1BADH1CADH1AADH7MAPT
SCHEMBL2802671 0.73 TDP1 (0.34) ALDH1A1MAPT
SCHEMBL29078899 0.73 MAOA (0.46) SMN1; SMN2ALDH1A1MAPT
SCHEMBL145175 0.71 CHRM2 (0.46) SMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL28376500 0.70 CHRM2 (0.45) SMN1; SMN2ALDH1A1MAPT
SCHEMBL28159956 0.70 MEN1 (0.35) CYP3A4MAPT
SCHEMBL28462277 0.70 L3MBTL1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US claimed
US-8011514-B2 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-09-06 US claimed
EP-2173491-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2010-04-14 EP claimed
EP-2040847-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES Georgia-Pacific Chemicals LLC (US) 2009-04-01 EP claimed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO claimed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US claimed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO claimed
US-9567655-B2 Processes for the separation of ores GEORGIA-PACIFIC CHEMICALS LLC (US) 2017-02-14 US disclosed
US-9150666-B2 Hydrolytically stable, hydrophilic adhesion-promoting monomers and polymers made therefrom ADA FOUNDATION (US) 2015-10-06 US disclosed
CN-104884392-A method for ore separation GEORGIA PACIFIC CHEMICALS LLC 2015-09-02 CN disclosed
WO-2014066237-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-05-01 WO disclosed
US-20140110621-A1 PROCESSES FOR THE SEPARATION OF ORES GEORGIA-PACIFIC CHEMICALS LLC (US) 2014-04-24 US disclosed
US-8252866-B2 Azetidinium-functional polysaccharides and uses thereof GEORGIA-PACIFIC CHEMICALS LLC (US) 2012-08-28 US disclosed
WO-2009005977-A1 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-01-08 WO disclosed
US-20080017552-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC CHEMICALS LLC (US) 2008-01-24 US disclosed
WO-2007149587-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2007-12-27 WO disclosed
EP-1838451-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC RESINS, INC. (US) 2007-10-03 EP disclosed
US-20070000839-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2007-01-04 US disclosed
US-20060151360-A1 Modified amine-aldehyde resins and uses thereof in separation processes GEORGIA-PACIFIC RESINS, INC. (US) 2006-07-13 US disclosed
WO-2006071672-A2 MODIFIED AMINE-ALDEHYDE RESINS AND USES THEREOF IN SEPARATION PROCESSES GEORGIA-PACIFIC CHEMICALS LLC (US) 2006-07-06 WO disclosed