Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665518 | 0.95 | APP (0.69) | APPALDH1A1ARRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17890756 | 0.93 | APP (0.67) | APPALDH1A1ARRAB9ASMN1; SMN2 | |
| SCHEMBL5538712 | 0.85 | LMNA (0.72) | APPRAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL11849334 | 0.83 | LMNA (0.69) | APPRAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL22198163 | 0.82 | KMT2A (0.60) | APPALDH1A1ARRAB9ASMN1; SMN2 | |
| SCHEMBL3686642 | 0.81 | TSHR (0.59) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL11324524 | 0.80 | LTA4H (0.74) | RAB9ASMN1; SMN2CYP1A2CYP2C19LMNA | |
| SCHEMBL8845456 | 0.80 | LTA4H (0.63) | APPRAB9ASMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL8736979 | 0.80 | LMNA (0.60) | ARRAB9ASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL891493 | 0.79 | FFAR1 (0.69) | APPRAB9ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536586-A | Pyrazole amide compounds and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |