Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolfenpyrad SCHEMBL26416 | 0.84 | RAB9A (0.57) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30150564 | 0.81 | RAB9A (0.46) | LMNARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL30150619 | 0.81 | LMNA (0.46) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30150594 | 0.79 | ACACB (0.47) | LMNARAB9ANPC1SMN1; SMN2HTT | |
| Tolfenpyrad SCHEMBL27825694 | 0.78 | MAPK14 (0.46) | LMNARAB9ANPC1SMN1; SMN2HTT | |
| Tolfenpyrad SCHEMBL16541149 | 0.78 | KMT2A (0.46) | LMNARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL9193836 | 0.78 | LMNA (0.54) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8077552 | 0.78 | LMNA (0.54) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL15220664 | 0.78 | LMNA (0.60) | LMNARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8069793 | 0.77 | LMNA (0.56) | LMNARAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536586-A | Pyrazole amide compounds and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |