SCHEMBL28926501

SCHEMBL28926501

CC(C)Oc1ccccc1-c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP2 P11137 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
EGFR P00533 1/20 0.38
SLC9A1 P19634 1/20 0.37
IRAK4 Q9NWZ3 2/20 0.37
CTSA P10619 1/20 0.36
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ACHE P22303 1/20 0.35
GCGR P47871 1/20 0.34
MAPK14 Q16539 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
TLR8 Q9NR97 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KCNN4 O15554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL22634093 0.85 GABRA1 (0.35) ALDH1A1GABRA1GABRB2NPSR1HDAC4
SCHEMBL29986284 0.85 APP (0.46) CA1CA2CA7CA9ALDH1A1
SCHEMBL28926527 0.78 KMT2A (0.36) EGFRALDH1A1KCNN4HDAC4HDAC8
SCHEMBL28859573 0.77 INPPL1 (0.40) ALDH1A1NPSR1FABP3FABP4
SCHEMBL31634047 0.75 IRAK4 (0.50) CA1CA2CA7CA9SLC9A1
SCHEMBL3632568 0.75 IRAK4 (0.50) CA1CA2CA7CA9SLC9A1
SCHEMBL28438073 0.75 GABRA1 (0.38) CA1CA2CA9GABRA1GABRB2
SCHEMBL28926436 0.75 LMNA (0.44) ALDH1A1ACHEGABRA1GABRB2NPSR1
SCHEMBL25338156 0.74 ROCK2 (0.55) CA1CA2CA7CA9
SCHEMBL31546214 0.74 ROCK2 (0.41) CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115385956-A Biaryl diphosphine ligands and transition metal complexes thereof 东莞市均成高新材料有限公司 2022-11-25 CN disclosed