Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960796 | 0.78 | HDAC1 (0.40) | HDAC1HDAC6HDAC3HDAC8NCOR2 | |
| SCHEMBL28658270 | 0.75 | PCSK9 (0.35) | HDAC1HDAC6HDAC3HDAC8NCOR2 | |
| SCHEMBL5731726 | 0.73 | CYP4Z1 (0.44) | CYP4Z1MAPTSMN1; SMN2CYP17A1CYP4F11 | |
| SCHEMBL5731731 | 0.73 | CYP4Z1 (0.44) | CYP4Z1MAPTSMN1; SMN2CYP17A1CYP4F11 | |
| SCHEMBL2524679 | 0.70 | DRD2 (0.47) | DRD2 | |
| SCHEMBL16443611 | 0.69 | MIF (0.52) | CYP4Z1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL3694163 | 0.67 | ADRA2A (0.42) | KMT2ALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3694161 | 0.67 | ADRA2A (0.42) | KMT2ALMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL18952166 | 0.65 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC8NCOR2 | |
| SCHEMBL22634155 | 0.64 | CA12 (0.45) | CYP4Z1CYP1A2CYP2C19CYP4F11CYP4F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463461-B | Cephem compounds, their preparation and use | 奈加-RGM制药有限公司 | 2021-11-19 | — | — | CN | disclosed |