Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 19/20 | 1.00 |
| ▸ | NOS3 | P29474 | 12/20 | 1.00 |
| ▸ | NOS2 | P35228 | 12/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928461 | 1.00 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928482 | 1.00 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928472 | 0.94 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928468 | 0.94 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928497 | 0.87 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928495 | 0.87 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928463 | 0.86 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL28928467 | 0.86 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL30062810 | 0.86 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL30054898 | 0.86 | NOS1 (1.00) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171402-A1 | Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors | UNIV NORTHWESTERN (US) | 2025-05-29 | — | — | US | disclosed |
| US-12240815-B2 | Potent and selective human neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2025-03-04 | — | — | US | disclosed |
| CN-115551832-A | Potent human neuronal nitric oxide synthase inhibitors | 西北大学 | 2022-12-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240815-B2 | Potent and selective human neuronal nitric oxide synthase inhibitors | NOS2, NOS1, NOS3 | NOS1 2/4885NOS3 3/4885NOS2 1/4885 |
| US-20250171402-A1 | Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors | NOS2, NOS1, NOS3 | NOS1 2/4885NOS3 3/4885NOS2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.