Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | VNN1 | O95497 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 4/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31575813 | 0.88 | GSK3B (0.61) | GSK3BVNN1P4HBFBP1KAT6A | |
| SCHEMBL40532 | 0.88 | GSK3B (0.61) | GSK3BVNN1P4HBFBP1KAT6A | |
| Fluorobenzene SCHEMBL28928520 | 0.84 | PARP1 (0.59) | GSK3BVNN1MAPK14 | |
| Benzoyl Chloride SCHEMBL8174168 | 0.77 | VNN1 (0.46) | GSK3BVNN1GPR139S1PR3KAT6A | |
| Bicarbonate SCHEMBL28730360 | 0.76 | ENPP2 (0.48) | GSK3BP4HB | |
| SCHEMBL4201889 | 0.76 | ATM (0.63) | GSK3BVNN1 | |
| SCHEMBL28979629 | 0.76 | PTPN11 (0.49) | — | |
| SCHEMBL15209661 | 0.76 | GSK3B (0.59) | GSK3BVNN1GPR139S1PR3KAT6A | |
| SCHEMBL29441888 | 0.76 | GSK3B (0.62) | GSK3B | |
| SCHEMBL60691 | 0.76 | GSK3B (0.62) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403579-A | Novel spiro derivative and application thereof | 上海拓界生物医药科技有限公司 | 2022-11-29 | — | — | CN | disclosed |